EFPF is a federated smart factory ecosystem and a digital platform that links different stakeholders of the digital manufacturing domain. The EFPF platform enables users to utilise innovative functionalities, experiment with disruptive approaches and develop custom solutions for specific needs. At the core of EFPF is an interoperable ‘Data Spine’ that provide open interfaces to support the integration of distributed systems and platforms with their integrated toolset and services. The EFPF federation is offered to the manufacturing and logistic companies as an open platform; to utilise the offered functionality, experiment with innovative approaches and develop custom solutions based on specific needs. The project demonstrates the power of federation through 3 embedded large scale pilots focusing on lot-size-one manufacturing and sustainable value networks in diverse sectors, while a cross-sectorial circular economy pilot is also incorporated. The results of the pilots are openly made available as lessons learned and best practices. The creation of the European smart factory ecosystem is supported by offering interested companies technical and financial support. The project is primarily composed of SMEs who have the agility to quickly react and adopt innovative solutions, while experience and market reach of big players such as Airbus and Siemens is also leveraged.